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KMID : 0376219790160020381
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Chonnam Medical Journal
1979 Volume.16 No. 2 p.381 ~ p.388
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The Comparative Study between Serum Alkaline Phosphatase and Gamma Glutamyl Transpeptidase Activities in Hepatobiliary Diseases.
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Abstract
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The activities of serum gamma-glutamyl transpeptidase and alkaline phosphatase were estimated in 102 cases of hepatobiliary diseases.
The relation between ¡-GTP and Al-P was also observed in above 102 cases.
The results were as follows;
A) There were 92 cases of hepatic diseases;
In 13 cases of acute viral hepatitis, the rate of abnormality of Al-P was 46.2% and that of ¡-GTP was 84.6%.
In 10 cases of chronic active hepatitis, the rate of abnormality of Al-P was 50.0% and that of ¡-GTP was 100%, and in 17 cases of chronic inactive hepatitis, Al-P was 52.9% and ¡-GTP was 83.4%.
In 23 cases of cirrhosis of the liver, the rate of abnormality of Al-P was 65.2% and ¡-GTP was 74.0%, and in 15 cases of malignancy of the liver, the rates of Al-P and; r-GTP were 73.3%.
In 7 cases of amebic liver abscess, the rates of abnormality of Al-P and ¡-GTP were 57.1%, and in 7 cases of pyogenic liver abscess, the rate of abnormality of Al-P was 71.4% and that of ¡-GTP was 100%.
B) In 10 cases of gall stone and cholecystitis, the rates of abnormality of Al-P and ; ¡-GTP were 90%.
In 102 cases of above hepatobiliary diseases, the rate of abnormality of Al-P was 62.7% and that of; ¡-GTP was 81.4%.
Above study showed that ¡-GTP was a sensitive diagnostic aid of hepatobiliary diseases.
And there was no correlation between Al-P and ¡-GTP in various hepatic diseases, but significant correlation (r=0.75, n=10) in gall stone and choleystitis (P=0.02.)
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KEYWORD
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